Transactions

Major Licensing Transactions

• Cross-License Agreement between GlaxoSmithKline and Asklepios BioPharmaceutical, Inc.
• Collaboration and License Agreement between Novo Nordisk and BioStratum Inc.
• License Agreement between DakoCytomation Denmark A/S and BioStratum Inc.
• Cross-License Agreement between AGTC, Inc. and Asklepios BioPharmaceutical, Inc.
• License Agreement between Athena Diagnostics, Inc., a subsidiary of Elan Pharmaceuticals Inc., and BioStratum Inc.
• License Agreement between Senju Pharmaceuticals and AcSentient, Inc.
• Trademark License Agreement between Bayer HealthCare LLC and Laboratories Gador S.A.
• License Agreement between University of West Virginia Medical Center and AcSentient, Inc.
• Collaboration Agreement between Dow Chemical Company and Nobex Corporation
• Collaboration Agreement between Bayer HealthCare LLC and Asklepios BioPharmaceutical Inc.
• Collaboration Agreement between Nobex Corporation and Biocon Ltd.
• License Agreement between Bayer HealthCare LLC and Bausch & Lomb Inc.
• License Option Agreement between Bayer HealthCare LLC and American National Red Cross
• License Agreement between Bayer HealthCare LLC and Clearant Inc.
• License Agreement between NanoCor Therapeutics Inc. and the University of Washington
• License Agreement between Crucell Holland B.V. and Talecris Biotherapeutics, Inc.
• License Agreement between Gilead Sciences, Inc. and Diatos S. A.
• License Agreement between Nobex Corporation and Dow Chemical
• License and Development Agreement between Talecris and Bausch & Lomb for development of recombinant products.
• License Agreement between Baxter and a biotech for a rFix product
• Collaboration and Development Agreement between Talecris Biotherapeutics, Inc. and Activaero GmbH

Mergers and Acquisitions

• Acquisition of Hemascan technology by Bayer Corporation from Arrowhead, LLC
• Sale of assets by AcSentient, Inc. to ISTA Pharmaceuticals, Inc.
• Sale of assets by Angiomics, Inc to Protein Design Labs, Inc.
• Acquisition by Aventis S.A. of secured debt interest in Scynexis, Inc.
• Sale of StarLink Logistics Inc. interest in Tech Pac LLC to Central Garden & Pet Company (Nasdaq:CENT)
• Divestiture of Tech Pac, LLC by Aventis to Central Garden & Pet Company
• Acquisition of stock of Raylo Chemicals, Inc. from Degussa SA by Gilead Sciences, Inc.
• Acquisition of Hemascan technology by Bayer Corporation from Arrowhead, LLC
• Sale of stock in TherapyEdge, Inc. to institutional investors
• Sale by StarLink Logistics, Inc. and Aventis Pharmaceutical of various real estate assets
• Acquisition of patented technology by NanoCor Therapeutics, Inc. from Johns Hopkins University

University Spin-Outs

• Massachusetts General, Harvard University - spin out of technology to NanoCor Therapeutics, Inc.
• Washington University the University of Utah and the University of North Carolina, Chapel Hill spin out of technology to University Genomics Inc.
• UNC-Chapel Hill - spin-out of technology to InnerOptic, Inc., a newly formed company
• UNC-Chapel Hill - spin-out of technology to Asklepios BioPharmaceutical, Inc., a newly formed company
• UNC-Chapel Hill - spin-out of technology to Karyogen, Inc., a newly formed company
• UNC-Chapel Hill- spin-out of technology to Invitrox, Inc., a newly formed company
• University of Eastern Virginia Medical School - spin-out of technology to AcSentient, Inc., a newly formed company)
• NanoCor Therapeutics Inc. spin-out from Asklepios BioPharmaceutical, Inc.
• UNC-Chapel Hill and University of Florida - license of technology to Molecular Orthopaedics, Inc.
• UNC-Chapel Hill - license of technology to Institute for OneWorld Health
• Duke University - license of technology to Angiomics, Inc.
• Duke University - license of technology to Novelios Pharmaceuticals, Inc.
• University of California - Berkeley - license of technology to Bayer HealthCare LLC
• North Carolina State University - license of technology to Silkore, Inc.
• Massachusetts General, Harvard University - license of technology to NanoCor Therapeutics, Inc.
• Washington University, the University of Utah and the UNC - Chapel Hill license of technology to University Genomics Inc.

Collaboration and Development Agreement

• Collaboration and Development Agreement between Talecris Biotherapeutics, Inc and Activaero GmbH
• Co-Development Agreement between Talecris Biotherapeutics, Inc and Bausch & Lomb Incorporated
• BioProcessing Services Agreement between Talecris Biotherapeutics, Inc. and Diosynth RTP Inc.
• Co-Development and License Agreement between Talecris Biotherapeutics, Inc. and Bausch & Lomb Inc.
• Development Agreement between Bayer HealthCare LLC and Mallinckrodt Baker, Inc.
• Development Agreement between Talecris Biotherapeutics, Inc. and British Biocell International (BBI)
• Product Agreement between Gilead Sciences, Inc. and Diatos S.A.
• Development and Manufacturing Agreement for blood and plasma screening reagents between Bayer Corporation and Roche
• Contract Manufacturing Agreements with DSM, ICOS, CMC, KBI and Diosynth
• Agreement for the manufacture, supply, and distribution of drugs by Sumitomo in Japan on behalf of a Gilead Sciences, Inc.
• Development Agreement for the development of monoclonal antibodies
• Co-Development and Manufacture Agreement for a plasma derived anthrax product
• Joint venture for the development and commercialization of a rFIX product
• Product Supply Agreement between Emergent Product Development Gaithersburg Inc. and Talecris Biotherapeutics, Inc.

Manufacturing and Distribution Agreements

• Manufacture and Distribution Agreement between Gilead Sciences, Inc. and Aspen Pharmacare Holdings Limited
• Purchase and Sale Back Agreement between Talecris Biotherapeutics, Inc. and and Kedrion S.p.A.
• Product Supply Agreement between and Talecris Biotherapeutics, Inc. and Emergent Product Development Gaithersburg Inc.
• European Product Sales Agreement between Talecris Biotherapeutics, GmbH and Bayer Biologicals S.r.l.
• Supply Agreement between Talecris Biotherapeutics, Inc and Bausch & Lomb Incorporated
• Supply Agreement between Gilead Sciences, Inc. and Degussa AG

Strategic Alliance Transactions

• Manufacturing Agreement of drugs between Bayer and B. Braun Medical Inc.
• Services Agreement between Bayer HealthCare LLC and Canadian Blood Services (CBS)
• Services Agreement between Talecris Biotherapeutics, Inc. and Bayer technology Services (BTS)
• Services Agreement between Talecris Biotherapeutics, Inc. and Bayer S.A. (SLA)
• Distribution Arrangements in China for Bayer Corporation
• Distribution Arrangements in Brazil for Bayer Corporation
• Distribution Arrangements in South America for Bayer

Financing

• Series C Preferred Stock Financing by BioResource International, Inc. to private investors
• Series A Preferred Stock Financing by Asklepios BioPharmaceutical, Inc. to private investor
• Series A Preferred Stock Financing by NanoCor Therapeutics, Inc. to private investor
• Series B Preferred Stock Financing by NanoCor Therapeutics Inc. to Medtronic, Inc.
• Series A Preferred Stock Financing by Inspiration Biopharmaceuticals, Inc. to Celtic Management, LP
• Sales of common stock in Inspiration Biopharmaceuticals, Inc. to private investors

Clinical Trials
Over the past 7 years, LSL has completed approximately 2500 agreements with various research institutions, CROs, and testing laboratory service providers including agreements with those groups listed below:

AAIPharma Accredo Health Group. Inc Acoda Therapeutics AcroMetrix acromion GmbH Clinical Research AcSentient, Inc Active Data Services, Inc. Agilent Ahepa Hospital Al-Achi and Freeman Alba BioPharm Allergy, Asthma & Immunology Associates, P.C. Allergy Associates of the Palm Beaches Alpha Therapeutic Corporation Amerisource Bergen Amersham Amylin, Inc. Analytic Insights Analytik Angiomics, Inc. Antonius Hospital AO Chieti (Italy) Aphios AppTec Arch Wireless Arrowhead, AHCDC Associates of Neurology in Pittsburgh Association of Hemophilia Clinic Directors of Canada Athena, Inc. Aventis Pharmaceuticals, Inc Aventis S.A. Axiom Clinical Research B & B Clinical Innovations, Inc. Bayerische Baylor College of Medicine BeroSearch GmbH BioAnalytika Laboratories, Inc. Biocore, Inc. BioFactor Inc. Biolex Inc. BioLink Life Sciences, Inc. BioMedicines, Inc. BioResource International, Inc. Bioscience Laboratories, Inc. BioSignal BioStratum Incorporated Blue Heron Botanical Remedy Research, Inc. Brigham and Women's Hospital Brown University BWA Consulting LLC Calvert Preclinical Campbell Alliance Can S.r.l. Medical Technology CarboGen Cardinal HealthCare Caritas St. Elizabeth's Medical Center of Boston CATO Centre Hospitalier Affilie Universitaire de Quebec Charles River Laboratories Charter Medical, Ltd. Children's Hospital of Michigan Children's Hospital of Philadelphia Children's & Women's Health Centre of British Columbia Children's Mercy Hospital Chiltern International Inc. Chrion Cincinnati Children's Hospital Cirrus Pharmaceuticals, Inc Clark Engineering Services, Inc. Clearant Consulting Cleveland Clinic Foundation ClinResearh GmbH Clintrak Pharmaceutical Services LLC Colburn & Associates Constantinescu - UK Cook Children's Medical Center Cornell University Covance CROfessional LLC DaVita Clinical Research Inc. Day and Zimmerman Deaconess Billings Clinic (England) Digene Corporation DiLan Clinical Packaging Duke University Dupont Emmes Corporation Enzon Erasmus Medical Center Errikos Dynan Hospital Exel Global Logistics, Inc. Experimental Pathologies Laboratories, Inc. EZ Associates, Inc. Finnish Red Cross Fletcher Allen HealthCare Flow Solutions Focus Technologies Foster Wheeler Frost and Sullivan Fuld & Company, Inc. GCP (Good Clinical Programs), GmbH Gefland Genesis Medical Marketing Consultants Gentofte German University Gilbert White

Girindus, Inc. Glaxo SmithKline Green Mountain, Inc. Haemacure Corporation Harvest Technical Services Health Management Systems Heart Core Hemophilia Center of Western Pennsylvania Henry Schein Inc. HerediLab Hospital of the University of Pennsylvania HR Medical Inc. Hygeia Associates ICON Clinical Research, L.P IDT InaMed Incell InfoStrength, Inc. InfuCare Consulting Int. GmbH Inkine Pharmaceutical InnerOptic Inveresk INSERM Institute for Asthma and Allergy Invitrogen Jeanette Miller Jenkins BioSciences, Inc. JL Company John Hopkins University Johnson & Johnson Kansas State University Karolinska Institute Karyogen Inc. Kendle International Kinderklinik Kirin Kingston General Hospital LabCorp LAF Adoption Program Lansmont Corp. Lasarettet I Trelleborg Universitat Koln MedTap Leiden University Medical Center Lighthouse Instrument LLC Loma Linda University London HSC Long Island Jewish MacroGenics Magellan Malmo University Hospital Manchester Children's Hospital Market Measures Interactive LP Mayo Foundation MDS McMaster University Meakins Christie Laboratories Med Augenklink der (The) Mendel Group Metrics, Inc. Military Medical University Monarch Labs Montreal General Hospital MorphoSys Morphotec, Inc. Mt. Sinai Medical Center National Analysts National Center of Neuroimmunology National Jewish Medical Center NCSU New York Presbyterian Hospital NHI Northeastern University Northwestern Memorial Hospital Novo Nordisk NuGenesis Octapharma AG Odem Omrix Optimed Research Origen Therapeutic Orion Clinical Services, Inc. Orthopedic Hospital Paul-Ehrlich Institute Pepitone Bershire Pharma Clinical PharmaNet PharmaResearch Pharmadule Phoenix Research Pilz Pivotal Labs Plasma Proteome Institute Postgraduate Institute for Medicine PPL Therapeutics PRA International Precision Biologic Prion Development Labs Quality Clinical Labs Quatern LLC Queen Elizabeth Hospital/NUB NHS Trust Quintiles Quorum Review Inc. Research Pharmaceutical Services Inc ResGen Rhode Island Hospital Richland Memorial Royal London Hospital

Royal Victoria Infirmary Sartorius AG Savant Technology Group Scripps Institute SemCo, Inc. SeraCare, Inc. Serentec Service du Pouget Hospital de la Timone Shearwater Sick Children�s Hospital Spectral Data Services, Inc. Springborn St. Louis Veterans Administration Medical Center St. Michael's Hospital Stanford University School of Medicine StarLink Logistics Inc. State University at Stony Brook Strategic Advantage Inc. Strategic Management Group. Sunshine Pharma SWB Consulting, Inc Sunshine Pharma SWB Consulting, Inc. Sylvia Lawry Centre for MS Tab Consulting Tailored Text Custom Publishing Technical University of Munich TherapyEdge, Inc. Thermo Lab Systems Titan Scan Technologies TNO Pharma Toronto General Hospital Trailblazer Studios Transfield Construction United BioSource Corporation University College - Dublin University Hospitals at Cleveland University Hospital Copenhagen University Hospital Alexandrovska - Sofia University of Chicago University of Colorado Hospitals University of Alabama Birmingham University of British Columbia University of California, Berkeley University of California, Davis University of California - Irvine University of California, Los Angeles University of California, San Diego University of Florida University of Hanover University of Iowa University of Kansas Medical Center University of Lund University of Maryland University of Miami University of Milan -Policlinico University of Minnesota University of Munich University of North Carolina at Chapel Hill University of North Carolina School of Medicine University of Nottingham University of Rochester University of South Carolina University of South Florida College of Medicine University of Texas University of Washington University of Wisconsin University of Virginia Vancouver Coastal Health Authority Vanderbilt University Ventria Bioscience Veterinary Infectious Disease Organization Vetter Pharma-Fertigung GmbH & Co. KG Viromed VivoMetrics Volt Services Group Wake Forest University Washington University School of Medicine Wayne State University WCI Wegeners West Pharmaceutical Services Western Wats Weill Medical College of Cornell University Winicker Norimed Winship Cancer Institute Yale University School of Medicine